No Kittle means the 49ers will be down three All-Pros on offense. The club figured to rely heavily on him while McCaffrey and ...

The San Francisco 49ers won’t have wide receiver Deebo Samuel for a couple weeks because of a calf injury he sustained late ...

San Francisco 49ers rookie wide receiver Jacob Cowing might have had his ‘welcome to the NFL’ moment during the team’s Week 2 ...

Head coach Kyle Shanahan on Wednesday confirmed in a press conference that Hufanga will get a full practice in to begin the ...

The San Francisco 49ers had a good start to their week of practice leading up to a Week 3 showdown with the Los Angeles Rams.

Wide receiver Brandon Aiyuk and quarterback Brock Purdy haven’t been able to get on the same page in the 49ers’ first two games. Aiyuk, who missed all of training camp because of dispute over a ...

A pair of San Francisco 49ers rookies made their debuts on the defensive side of the ball in Week 2. Cornerback Renardo Green and safety Malik Mustapha both saw action on defense against the Minnesota ...

Thirteen other former 49ers were nominated for the Pro Football Hall of Fame's 2025 class. Quarterback Eli Manning, running ...

The San Francisco 49ers may need to do something about their backfield depth. Running back Jordan Mason has racked up 48 ...

The San Francisco 49ers officially have a significant injury problem on their hands. Running back Christian McCaffrey is out ...

Malik Mustapha is not one of the favorites to win the NFL Defensive Rookie of the Year award this season, at +10000 (34th-ranked odds).Mustapha has been a big piece of the 49ers’ defense in ...

One spot they’ve yet to fill is the one vacated by running back Christian McCaffrey when he was placed on Injured Reserve.