The Indianapolis Colts will play the Miami Dolphins on Sept. 7, a highlight of their 2025 season. The Colts' full NFL schedule is listed below, and we've provided info on tickets as well. Date: Sept. 7 at 1 p.m. ET

On paper, the Colts will have the 12th-easiest schedule, according to Sharp Football. This includes facing six different playoff teams from last season, with five of those games coming on the road. The Colts also play only two teams that picked inside the top 10 in this year's NFL draft.

Due to an insensitive joke towards Dolphins receiver Tyreek Hill and Microsoft rights violation, the Indianapolis Colts scrapped their Minecraft-themed 2025-2026 NFL schedule release video.