The San Francisco 49ers have been struggling with injuries all season, and it finally caught up with them. On Sunday, they ...

San Francisco 49ers head coach Kyle Shanahan offered a cryptic update on the return of quarterback Brock Purdy.

The San Francisco 49ers will not open wide receiver Brandon Aiyuk's 21-day practice window ahead of their Week 9 game vs. the ...

Brock Purdy missed his fourth straight game on Sunday and head coach Kyle Shanahan discussed at his Monday press conference ...

On Friday, Shanahan told David Lombardi of SFStandard.com that Aiyuk's 21-day practice window may open this week, but even if it doesn't, the 49ers currently are in "week-to-week mode" with the wide ...

The San Francisco 49ers are optimistic about the progress one injured star is making, but his return won't happen in Week 9 ...

NFL Network Insider Tom Pelissero reporting San Francisco 49ers could open wide receiver Brandon Aiyuk's practice window this ...

NFL Network's Kurt Warner on keys to quarterback Jaxson Dart's early success with the New York Giants. "NFL GameDay Morning" ...

The San Francisco 49ers, led by quarterback Mac Jones, face the Houston Texans, led by quarterback C.J. Stroud, on Sunday, ...

If the 49ers win Sunday in Houston, they’ll match their overall win total from last season and they’ll be alone atop the NFC ...

The San Francisco 49ers have not been healthy this season, and with Fred Warner and Nick Bosa out for the season, they will ...

Explore why 49ers' Christian McCaffrey is considered the most disappointing player this season despite leading the NFL in ...