The 49ers will need to prepare well for this challenging area against Texans if they want any chance of winning.

Change was expected to come to the Texans after back-to-back postseason appearances, but six games into the season and it looks like regression.

The Houston Texans will be without star wide receiver Nico Collins for Sunday's Week 8 matchup against the 49ers.

San Francisco 49ers quarterback Brock Purdy has been ruled out for his team's Week 8 matchup against the Houston Texans amid his recovery from turf toe.

HOUSTON – Derek Stingley Jr. lined up across from Seattle Seahawks star wide receiver Jaxon Smith just four times Monday night. That was his coverage assignment, and the Texans All-Pro cornerback emphasized he always does what he’s coached to do, not simply what he feels like doing.

Here's where the Texans stack up in FPI ratings entering their Week 8 showdown against the San Francisco 49ers

Colin Cowherd picks his best predictions for Week 8 of the 2025/26 NFL season, including the Baltimore Ravens over the Chicago Bears, the New England Patriots over the Cleveland Browns, and the Houston Texans beating the San Francisco 49ers.

Houston coach DeMeco Ryans will face his former boss San Francisco coach Kyle Shanahan for the first time Sunday when the Texans host the 49ers.