Texans head coach DeMeco Ryans is a former 49ers defensive coordinator under Kyle Shanahan, so San Francisco knows how ...

Mac Jones has been a massive addition to the San Francisco 49ers this offseason. The team is 4-1 when he starts this season, ...

The 49ers had the ball for only 18 ½ minutes Sunday. It's an apt analogy for Mac Jones, whose time as San Francisco's ...

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 2.5-point favorites, according to the latest 49ers vs.

San Francisco 49ers quarterback Mac Jones locates tight end George Kittle for a 17-yard sliding grab against the Houston ...

Talking to NBC Sports Bay Area's Matt Maiocco, San Francisco coach Kyle Shanahan shared what Mac Jones has to do for the ...

The Texans lost to the Seattle Seahawks 27-19 on Monday night even though Anderson scored the first touchdown of his NFL ...

ESPN BET Sportsbook is owned and operated by PENN Entertainment, Inc. and its subsidiaries ('PENN'). ESPN BET is available in ...

San Francisco 49ers quarterback Brock Purdy has been ruled out for his team's Week 8 matchup against the Houston Texans amid ...

Brock Purdy's injury update opens a financial opportunity for San Francisco 49ers backup quarterback Mac Jones.

Jones completed 19 of 32 passes for 193 yards with two touchdowns and one interception while adding two rushes for 23 yards in the 49ers ' 26-15 loss to the Texans on Sunday. He also threw a two-point ...