With Brock Purdy continuing to miss time for the 49ers due to injury, Mac Jones has a great opportunity to maximize his earnings.

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. Before you make any Texans vs. 49ers picks, make sure to check out what the SportsLine Projection Model has to say.

The Texans lost to the Seattle Seahawks 27-19 on Monday night even though Anderson scored the first touchdown of his NFL career. Anderson had a strip-sack of quarterback Sam Darnold and recovered the fumble in the end zone.

The 49ers will go another week without starting quarterback Brock Purdy, who’s continuing to deal with a toe injury. While Purdy was a limited participant in practice this week, the team has ruled him out for Sunday’s game in Houston. Backup Mac Jones will start again in Purdy’s place.

San Francisco 49ers tight end Jake Tonges catches a 2-yard touchdown pass on a crossing route from quarterback Mac Jones against the Houston Texans.

San Francisco 49ers coach Kyle Shanahan provided an update on quarterback Brock Purdy's injury, while Mac Jones suffered a knee contusion.