Roswell Park has a new tool in cancer detection. On Wednesday, Roswell Park announced a new “EDDY” mobile unit that is ...

Bills vs. Buccaneers in Week 11 of the 2025 NFL season will air nationally on CBS, with Ian Eagle (play-by-play), JJ Watt ...

West Herr provided hundreds of turkeys to Western New York families on Thursday in a holiday food drive. Buffalo Acting Mayor ...

Buffalo was buzzing on Friday night with not one but two major events drawing crowds downtown. Buffalo businesses got “a ...

NFL football continues with Week 11. Who plays NFL games today? What is the NFL TV schedule? See every NFL game's start time ...

Collins Correctional Facility, a medium-security prison in Erie County, will consolidate by the end of the fiscal year, the ...

On “Buffalo Beyond the Box Office,” News 4 anchor Jordan Norkus and senior executive producer Natasha Yurek showcase theater and film projects across Western New ...

Multiple fire units were on the scene Monday night after a massive fire broke out inside a home in Armstrong County.

Josh Allen was sacked eight times and threw two interceptions and the Bills turned the ball over three times to lose to the ...

Through 2024, a total of eight holiday films aired on television with local connections. This year, 10 holiday movies were ...

Tucker’s six-yard TD run in the third came after Mecole Hardman fumbled a punt at the Buffalo 43, and after a Matt Prater ...

The red-hot Rams will host the Buccaneers in a battle of NFC playoff hopefuls on Sunday Night Football. Here's how to watch ...