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Aldosterone dysregulation contributes to hypertension. Lorundrostat is an aldosterone synthase inhibitor, but data on its efficacy and safety in patients with hypertension are limited. In this ...
Treatment with fidanacogene elaparvovec, a recombinant adeno-associated virus (AAV) vector developed for the treatment of hemophilia B, led to sustained expression of the high-activity factor IX ...
Enteral nutrition is defined as the provision of essential nutrients through an enteral tube to prevent or treat disease-related malnutrition in patients who are unable to consume adequate ...
Tecovirimat is available for the treatment of mpox (formerly known as monkeypox) in Europe and the United States, on the basis of findings from efficacy studies in animals and safety evaluations ...
A 79-year-old woman was evaluated for cough and weight loss. Chest imaging and thoracentesis findings confirmed the presence of an exudative right pleural effusion. A diagnosis was made.
In the initial months of the Trump administration, numerous executive orders have led to a chaotic dismantling of U.S. foreign-assistance and global health efforts. These orders have already had ...
Atrial fibrillation is the most common cardiac arrhythmia that is encountered in clinical practice, with some 4.5% of the general population affected in the United States. It has been nearly 30 ...
For patients with lupus nephritis, a recent phase 2 trial showed that the addition of obinutuzumab to standard therapy was associated with a significantly better renal response than placebo.
Tecovirimat is available to treat mpox in the United States and Europe, but evidence for its efficacy and safety from randomized, controlled trials has been lacking. New research findings are ...
Catheter-based pulmonary-vein isolation with thermal ablation is effective for atrial fibrillation. How pulsed field ablation, a nonthermal method, compares with cryoablation when atrial ...
Authors may complete the Presubmission Inquiry form below to learn about the suitability of proposed manuscripts or to propose review article topics. An NEJM Editor will generally respond by email ...
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