States have responded to increasing health care consolidation by enhancing their review of mergers and acquisitions. But some states have carved out certain academic medical centers from such ...

Medical evidence comes in the form of population statistics, but patients behave like people, each one unique. Physicians ...

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...

Data are needed on the effect of oxygen delivered through a high-flow nasal cannula, as compared with standard oxygen therapy, on intubation and mortality in patients with acute hypoxemic ...

Recent changes in U.S. vaccine policy are sowing confusion and threatening the health of children and the wider population.

In patients with refractory systemic lupus erythematosus, in vivo generation of CD19 CAR T cells by means of lipid nanoparticles led to B-cell depletion, reduced disease activity, and no major toxi ...

A 69-year-old man presented with a history of gradual thickening and wrinkling of the skin on the left side of his face. The physical examination showed hyperkeratosis with accentuated ridging, ...

As a legacy of African enslavement, structural racism affects both population and individual health in three interrelated domains: redlining and racialized residential segregation, mass incarceration ...

Explore this issue of The New England Journal of Medicine (Vol. 390 No. 3).

To the Editor: Vitiligo is a depigmenting skin disorder that can have a substantial effect on patients’ quality of life. In their report on two phase 3 trials of ruxolitinib cream (Topical Ruxolitinib ...

To the Editor: Sanyal et al. (Oct. 21 issue)1 add important new data to our understanding of the natural course of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis (NASH). A substa ...