News

EMBO Press2d
Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
Pathway-focused metabolite ratio-based analysis of 49 tumor and 8 normal epithelial cell lines grown in their respective ...
EMBO Press2d
The making and breaking of insect endogenous retroviruses
Recent work by Senti et al (2025) reports that retrotransposons and endogenous retroviruses occupy specific spatiotemporal ...
EMBO Press3d
MPS1 promotes timely spindle bipolarization to prevent kinetochore-microtubule attachment errors in oocytes
Meiotic errors in oocytes cause egg aneuploidy. This study shows that kinetochores employ MPS1 kinase to promote timely ...
EMBO Press8d
IL-36 signaling as a drug target in Crohn’s disease patients with IL36RN mutations
This study investigates the potential involvement of mutations in the IL-36 receptor antagonist (IL36RN, IL-36RA) in the ...
EMBO Press11d
Ontology-guided clustering enables proteomic analysis of rare pediatric disorders
This discovery-driven proteomics study of a pediatric population - including rare diseases - introduces a SNOMED CT-guided ...
EMBO Press10d
Parthenolide disrupts mitosis by inhibiting ZNF207/BUGZ-promoted kinetochore-microtubule attachment
The antimitotic properties of parthenolide, a natural compound with known anticancer activity, have been largely ...
EMBO Press9d
A protein-based classifier for differentiating follicular thyroid adenoma and carcinoma
A proteomics-driven 24-protein classifier improves the differentiation of thyroid adenoma and carcinoma, retrospectively and ...
EMBO Press11d
Elevated TGF-β1 impairs synaptic and cognitive function through activation of Smad2/3-Sp1 pathway in AngII-related hypertension
Increased TGF-β1 promotes the phosphorylation and nuclear translocation of Smad2/3, sequentially activating the transcription ...
The EMBO Journal2d
Synergy and antagonism in the integration of BCR and CD40 signals that control B-cell population expansion
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...
The EMBO Journal2d
Targeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cells
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. TP53 mutations in AML confer resistance to CAR ...
The EMBO Journal2d
Combined dendritic cell and anti-TIGIT immunotherapy potentiates adaptive NK cells against HIV-1
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Natural Killer (NK) cells are promising ...
The EMBO Journal1d
High order expression dependencies finely resolve cryptic states and subtypes in single cell data
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Single cells are typically typed by clustering ...