Despite coming off a bye, a massive list of Colorado Buffaloes players are expected to miss Saturday's matchup against the Utah Utes due to injury. Seventeen Bu

The Colorado Buffaloes are gearing up for their eighth game of the 2025 season this Saturday, October 25, at 8:15 p.m. MT, when they face the Utah Utes in Salt Lake City. Utah enters the matchup as a 13.5-point favorite on its home field.

Junior quarterback Devon Dampier popped up on the availability report Wednesday night as "questionable," which will fuel the possibility of Ficklin, a true freshman, starting against Colorado (8:15 p.m. MDT, ESPN) in a game the Utes must win to keep their fading Big 12 championship game hopes alive.

The Colorado Buffaloes will look to improve to .500 on the season when they go on the road to play the 5-2 Utah Utes. Colorado and coach Deion Sanders are seeking their first road win of the 2025 season.

Colorado coach Deion Sanders entered the wild during his team's bye week but now faces another tough night game at Utah on Saturday

Utah might debut a new starting quarterback when the Utes host Colorado on Saturday in Salt Lake City. Devon Dampier sustained an ankle injury during the Utes' 24-21 loss to BYU last weekend. Dampier finished out the game, but Byrd Ficklin was inserted for designed QB run plays late in the second half.

Deion Sanders and the Colorado Buffaloes await a critical Big 12 showdown with Utah. With the Utes having major QB injury news, a win could also leapfrog CU ahead of the Utes in the conference standings.

Pregame analysis and predictions of the Colorado Buffaloes vs. Utah Utes NCAAF game to be played on October 25, 2025 on ESPN.