Nervous system functions, from motion to perception to cognition, depend on the active zones of neural circuit connections ...

The regulation of neuronal excitability and the maintenance of an appropriate balance between excitation and inhibition are central to brain function. Inhibitory synaptic transmission, predominantly ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

Synaptic transmission tenets challenged Two distinct pools of synaptic vesicles appear to be involved in the spontaneous release of neurotransmitters and in neurotransmission triggered by a stimulus, ...

Genetic deficiency of otoferlin, a protein critical to synaptic transmission by the sensory hair cells of the ear, causes congenital deafness. Medicines to treat the condition are lacking; ...