Intermediate filament proteins constitute a diverse family of cytoskeletal biopolymers. They assemble into durable yet dynamic networks that confer mechanical support, organise subcellular ...

Just as the skeleton and muscles move the human body and hold its shape, the cells of the body are stabilized and moved by a cellular skeleton. This cellular skeleton is a dynamic structure, ...

Numerous species of prokaryotic and eukaryotic origin are predicted to encode coiled-coil intermediate filament (IF) or IF-like proteins 1,2,3,4. However, the first IF to be studied was of metazoan ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an estrogen independent manner. Targeting vimentin and/or the long ...

The symptoms of neurodegenerative diseases like Alzheimer’s, frontotemporal dementia, and chronic traumatic encephalopathy (CTE) are different, but they have one feature in common: the presence of ...