Microglia are the hot ticket in Alzheimer’s research these days, with a stream of studies showing that these cells can worsen or lessen pathology. In this balance, their receptor TREM2 acts as a pivot ...
Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer's disease. Knowing the shape of the molecule -- and ...
Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer's disease. Knowing the shape of the molecule -- and ...
Known as a keen sensor of mischief, TREM2 sets off microglial responses to Aβ, tau, and other markers of neuronal distress. A new study now adds pathological TDP-43 to that list. In a paper published ...
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) is a membrane protein expressed on immune cells and associated with neurodegenerative diseases, such as Alzheimer’s disease. Several studies ...
Scientists have detailed the structure of a molecule that has been implicated in Alzheimer's disease. Knowing the shape of the molecule -- and how that shape may be disrupted by certain genetic ...