Molecular residual disease (MRD) detection using bespoke circulating tumor DNA (ctDNA) assays in localized soft tissue sarcoma (STS): A multicenter study. Phase II study to evaluate surufatinib in ...

Since somatic oncogenic variants result from the interaction between genetic background and the environment, driver genes are expected to differ in the LAC population compared with other geographic ...

Genetic variation is the foundation of human diversity, enabling differences in traits such as height, eye color, or blood type. Some sequence variants also cause inherited diseases, including sickle ...

Genetic risk models, including PREMMplus and BOADICEA/CanRisk, refine breast cancer risk assessment by incorporating genetic status and polygenic risk scores. Challenges in classifying gene variants, ...

In a recent study published in Nature Genetics, researchers performed saturation genome editing (SGE) of the BRCA1-associated protein-1 gene (BAP1), whose dysfunction is related to cancer and impaired ...