Mineralocorticoid receptors (MR) are expressed in epithelial and non-epithelial tissues, including the kidney, colon, brain, heart, vasculature, and adipose tissue. MR activation in the kidney induces ...
Disruption of sodium homeostasis has a central role in the development and progression of chronic kidney disease (CKD). Excess dietary sodium can overwhelm regulatory mechanisms and amplify pathways ...
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