The DNA mismatch repair (MMR) pathway is fundamental to genomic stability, recognising and correcting replication errors that escape the proofreading activity of DNA polymerases. Central to this ...
New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...
Base excision repair (BER) is a fundamental pathway that safeguards genomic integrity by detecting and removing small base lesions arising from oxidation, alkylation, deamination or spontaneous base ...
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