circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

To understand the human genome, scientists focused on protein-coding genes and their functions for decades. This has given us invaluable knowledge about the inner workings of the human body. But that ...

The expression of genes has to be very carefully controlled by cells; serious problems can arise when genes are expressed in the wrong places, at the wrong times, or at the wrong levels, for some ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

Researchers have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes. The team discovered much higher levels of lncRNAs in the testes than had ...

Scientists have identified a new RNA molecule that may play a key role in improving survival in cancer patients.

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

Scientists have found new genetic causes for diabetes in babies—in a part of the genome that has historically been overlooked ...