The Global Antibiotic Research and Development Partnership (GARDP) said yesterday that an international clinical trial ...

Given the inconsistencies in guideline recommendations on optimal timing of empirical antibiotic discontinuation, this study aimed to systematically review and assess the efficacy and safety of ...

Neonatal sepsis is a leading cause of infant morbidity and mortality in low- and middle-income countries (LMICs), yet despite ...

Sepsis is one of the most commonly encountered pathologies in the neonatal intensive care unit (NICU) and is associated with significant morbidity and mortality. 1 Many infants with sepsis develop ...

A major multi-country study has found that WHO-recommended first-line antibiotics for neonatal sepsis are likely to be effective in only one-quarter of infections in low- and middle-income countries ...

Sepsis leads to life-threatening organ failure due to dysregulated host responses to infection and presents uniquely across age groups. Neonatal sepsis, affecting infants in their first 28 days, ...

A study presented at ESCMID Global 2025 has uncovered the potential of interleukin-6 (IL-6) as a powerful diagnostic biomarker for the early detection of sepsis in high-risk patient groups, including ...

An international clinical trial co-led by UCL (University College London) researchers will evaluate much-needed new antibiotic combinations for newborn babies with sepsis. The trial, which has started ...

Among the 981,869 children, 0.8% were diagnosed with sepsis and less than 0.1% diagnosed with meningitis; overall, 1.2% of children developed epilepsy during the study period. Children with clinically ...

LISBON, Portugal — A shift toward broader-spectrum antibiotics and increasing antibiotic resistance has led to high levels of mortality and neurodevelopmental impacts in surviving babies, according to ...

To rapidly communicate information on the global clinical effort against Covid-19, the Journal has initiated a series of case reports that offer important teaching points or novel findings. The case ...

Despite the mortality and long-term sequelae occurring secondary to neonatal meningitis, past studies have shown that lumbar punctures (LPs) are not done in neonates as often as they should be. This ...