Researchers at UNSW Sydney have pinpointed genes that may play a causal role in vascular dementia, offering promising leads for drug development. The study used Mendelian randomization to analyze over ...

Mendelian randomization (MR) is transforming how scientists uncover causal links in health research by using genetic variants as natural experiments. Recent advances are tackling challenges like rare ...

Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including ...

Salt intake showed no genetic causal link to gastric cancer risk. Read more on the Mendelian randomization findings.

A new study identifying 56 non-clinical risk factors associated with sudden cardiac arrest (SCA), spanning lifestyle, physical measures, psychosocial factors, socioeconomic status, and the local ...

A small potential link was found between female infertility and breast cancer, but not with other gynecological cancers. Multiple analysis methods, including Mendelian randomization and RAPS, were ...

Using MR-SPI and AlphaFold3, scientists unravel the molecular underpinnings of Alzheimer’s disease, identifying key protein changes that could reshape future treatments. Study: Deciphering proteins in ...