In a recent study published in Cell, researchers examined the wealth of information available regarding the heterogeneity of tissue macrophages. They pursued a conceptual framework for better ...

Tissue-resident macrophages can originate from embryonic or adult hematopoiesis. They play important roles in a wide range of biological processes including tissue remodeling during organogenesis, ...

Even its name is a testament to how enigmatic the tingible macrophage has been. Tingible, which means stainable, certainly gives no clues to its functions – but was, at least, one thing that was known ...

Macrophages are the specialized phagocytic cells that respond to toxic particle depositions to exert inflammatory and clearance responses. These long-lived immune cells engulf foreign substances like ...

As a chronic pro-inflammatory disease, obesity is closely associated with the development of various diseases such as type 2 diabetes, cardiovascular disease and cancers. Obesity is now a major ...

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells. Yet despite their innate "combat" capabilities ...

Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium urate crystals, or MSUc; CPPD disease, another inflammatory joint disease ...

The understanding of how macrophages regulate their response to toxic particles via two independent pathways could uncover therapeutic opportunities to quell inflammation BIRMINGHAM, Ala. – Human ...