Notre Dame will always be compared to USC as USC will always be compared to Notre Dame. That's just how rivalries have always gone and will always go. The matchup between the two happens on Thanksgiving weekend this year and could be huge in determining College Football Playoff bids.

Michigan State (3-0, 1-0 Big Ten) plays at Boston College (2-1, 1-0 ACC) on Saturday (8 p.m., ACC Network) to kick off a very difficult stretch of the schedule. Here are five things to watch in the game and a final score prediction: The Spartans already pulled off an upset on the road by rallying late for a 27-24 win at Maryland in Week 2.