Hemochromatosis is one of the most common genetic conditions and can be life-threatening — here's how it manifests.

The need for regular blood transfusions, as well as underlying processes in MDS, can result in iron overload. If left untreated, excess iron can cause widespread damage to organs throughout the body.

Patients with serum ferritin levels higher than 1000 μg/L show a 91% increased risk for any fracture, with a doubled risk for vertebral and humerus fractures compared with those without iron overload.

Saturation of TfR1 leads to the dissociation of Hfe and the binding of the alter to the TfR2, which in turn influences the binding of BMP6 to its receptors on the membrane. Increased liver iron ...

Study reveals liraglutide's potential to regulate iron metabolism and improve glucose tolerance in a mouse model of hereditary hemochromatosis and obesity. Study: Liraglutide Impacts Iron Homeostasis ...

β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ineffective erythropoiesis and severe anemia. Patients with ...

USC researchers have uncovered a hidden driver behind the early and severe onset of Alzheimer's in people with Down syndrome: iron overload in the brain. Their study revealed that individuals with ...

Merganser Biotech, a drug licensing and development startup, has secured funding from a consortium that includes BioAdvance, the Biotechnology Greenhouse of Southeastern Pennsylvania and individual ...