While type I interferon (IFN) is best known for its key role against viral infection, accumulating preclinical and clinical data indicate that robust type I IFN production in the tumor ...

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused over 260 million cases of coronavirus disease 2019 (COVID-19) along with five million deaths. It has affected different ...

In a recent study published in Science Immunology, researchers investigated whether individuals with breakthrough infections of severe coronavirus disease 2019 (COVID-19) pneumonia demonstrated normal ...

Xeroderma Pigmentosum C (XPC) is a DNA damage recognition protein central to the global genome nucleotide excision repair (GG-NER) pathway, where it acts as a primary sensor of UV-induced DNA lesions.

Known as first responders to viral infection, Type I interferons may also play a part—for better or worse—in neurodegenerative disease. At AD/PD 2022, held March 15-20 online and in Barcelona, Spain, ...

CHICAGO — The use of a clinically validated flow cytometry test can assess type 1 and type 2 interferon activity in children with various pediatric inflammatory diseases to evaluate and monitor their ...

New research from The Wistar Institute's Montaner lab—led by Wistar Executive Vice President, director of the HIV Cure and Viral Disease Center, and Herbert Kean, M.D., Family Professor, Luis Montaner ...

Please provide your email address to receive an email when new articles are posted on . “These findings suggest that IFN-I blocking agents may be particularly effective in treating skin manifestations ...