Eukaryotic translation elongation factors orchestrate the delivery of aminoacyl-tRNAs to the ribosomal A-site during protein synthesis, yet their roles extend far beyond housekeeping. Among these, the ...

Eukaryotic protein synthesis is coordinated by a suite of translation factors that regulate initiation, elongation and termination. Initiation involves assembly of a pre-initiation complex, ...

Life depends on the precise functioning of several proteins synthesized in cells by ribosomes. This diverse set of proteins, known as a proteome, is maintained by the robust translation elongation of ...

In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...