Most if not all organs in mammals have adult stem cells that have some capacity to make and repair tissues throughout the lifetime of the organism. To understand how stem cells achieve these functions ...

Epithelial cells are the most common cell type in all animals, forming the sheets and tubes that compose most organs and tissues. Apical–basal polarity is essential for epithelial cell form and ...

Compared to cellular and organismal homeostasis, tissue homeostasis is not yet well understood. (Medzhitov) Cells have three division-of-labor relationships: (1) cell types perform different functions ...