The mammary gland epitomises a dynamic tissue in which epithelial cells interact intimately with a specialised extracellular matrix (ECM) to control development, morphogenesis and homeostasis. In the ...
The basement membrane is a specialised form of extracellular matrix that underlies epithelial and endothelial cell layers, forming a thin yet robust scaffold composed primarily of laminins, type IV ...
Researchers at Children's Hospital Los Angeles have discovered a key difference between the two main types of rhabdomyosarcoma—paving the way for more targeted treatments. The study, led by JinSeok ...
Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical instruments like microscopes and spectrometers. Fiore, a physicist by training, came ...
Peptide-based signaling systems continue to occupy a central role in modern biochemical inquiry, particularly in areas concerned with extracellular matrix (ECM) dynamics and structural protein ...
Researchers have shown that activation of the protein YAP, known to help cancer cells survive treatment, behaves very differently in cell culture models depending on how they are grown in the lab, ...
Researchers headed by a team at the University of Texas at Dallas’ Center for Advanced Pain Studies (CAPS) have made a fundamental discovery about a key mechanism that enables nervous system ...
Gastrointestinal (GI) malignancies—including esophageal, gastric, colorectal, hepatic, and pancreatic cancers—constitute a major global health burden and ...
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