For decades, animal models have been the gold standard for preclinical testing of potential drugs. Yet, even the best animal models are not perfect. For example, small rodent species with engrafted ...

Research and drug discovery are undergoing a transformation, driven by the rise of 3D cell culture models that better replicate human biology. Unlike traditional 2D cultures and animal models, which ...

Advancing neurological disorder research requires model systems that more accurately reflect the human brain. 3D cell cultures, such as organoids and spheroids, have emerged as game-changers by better ...

A new 3D human brain tissue platform developed by MIT researchers is the first to integrate all major brain cell types, including neurons, glial cells and the vasculature into a single culture. Grown ...

Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

In a lab rack that looks more like a high-end audio system than a server, clusters of human brain cells are quietly learning ...

Pancreas development in pigs resembles humans much more closely than does the established mouse model. An international team headed by Helmholtz Munich and the German Center for Diabetes Research (DZD ...