The discovery of Hoogsteen base pairs, an alternative pairing mode to the canonical Watson–Crick structure, has significantly broadened our understanding of DNA dynamics. This conformation, in which ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

Base pairs are at the heart of molecular biology information. Recognized ever since their discovery by Watson and Crick in 1953, the base pair provides, among other things, rules for copying DNA, ...

Study Shows How Melting Point Analysis Infers the Presence of and Identifies SNPs The melting temperature (T m) of a PCR product is dependent on both the length and sequence of the DNA. Melting curve ...

COLUMBUS, Ohio -- Shape-shifters aren't just the stuff of fiction, they're real--and they're inside our DNA. In the Feb. 1 issue of the journal Nature, researchers describe how two normally mismatched ...