How many ways can a troponin assay come up with a false positive or a false negative? In this episode of AP Cardiology, Andrew Perry, MD, tallies it up with Robert Christenson, PhD, of the University ...

Interference in laboratory assays is a concern since it can positively or negatively influence test results, which can affect patient care. Interferents could be endogenous or exogenous compounds.

Luminescence and fluorescence-based assay methods prevail in modern HTS. Although invaluable as technologies, the problem of compound-related assay interferences such as quenching, auto-fluorescence, ...

You run the assay. The values come back off. Not catastrophically wrong, just inconsistent enough to make you doubt everything. You've checked the protocol twice. The kit hasn't expired. But the CV is ...

The US Food and Drug Administration is reminding the medical community about the potential for high levels of biotin—or vitamin B7—to interfere with certain lab tests, including cardiac troponin ...

Immunoassays used for human in vitro diagnostics (IVD) often use animal-sourced antibodies to recognize specific disease markers. A small percentage of individuals, however, may have antibodies in ...

Avoiding immunoassay interference requires blockers to be included in every immunoassay. Historically, animal-based interference blockers have been used to improve assay accuracy; however, they are ...

There is a growing list of medications known to adversely affect thyroid function or interpretation of the results of standard thyroid laboratory testing. Many of these drugs are commonly used ...

Luminescence screening assays have become a central component of modern drug discovery workflows, particularly in high-throughput screening (HTS) environments. These assays enable rapid, sensitive ...