Conversion of IgG antibodies to IgM broadens antibacterial activity

Researchers at UMC Utrecht have discovered that converting monoclonal antibodies from the IgG to the IgM isotype can ...
The New England Journal of Medicine

Neonatal Fc Receptor — Biology and Therapeutics

Details and references regarding individual diseases are provided in the Supplementary Appendix. CIDP denotes chronic inflammatory demyelinating polyneuropathy, Covid-19 coronavirus disease 2019, and ...
The New England Journal of Medicine

Nipocalimab in Early-Onset Severe Hemolytic Disease of the Fetus and Newborn

In early-onset severe hemolytic disease of the fetus and newborn (HDFN), transplacental transfer of maternal antierythrocyte IgG alloantibodies causes fetal anemia that leads to the use of high-risk ...
Medical News Today

What is a hepatitis A IgG-positive and IgM-negative result?

Hepatitis A blood tests check for immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies. An IgG-positive and IgM-negative result may suggest immunity to hepatitis A. A doctor may request a ...
ascopubs.org

Clinical analysis of AFFINITY trial: Quantification of tumor-specific antibodies and immune cell activation following Aliya PEF ablation in stage IV cancer patients.

Novel lipid metabolism-related gene signature associated with clinical and immune features in lung adenocarcinoma patients experiencing lymph node metastasis. Mean fold-change vs. baseline (p < 0.05) ...