Adenosine is a neuromodulator with receptor-mediated effects. De novo synthesis of adenosine in brain is low 1; thus, adenosine is primarily derived from dephosphorylation of ATP. In physiological ...

Uridine adenosine tetraphosphate (Up4A) is a dinucleotide recognised for its dual purinergic properties that markedly influence vascular tone. In the context of diabetes, vascular dysfunction often ...

The regulation and function of sleep is one of the biggest black boxes of today's brain science. A new paper finds that rapid eye movement (REM) sleep is suppressed by adenosine acting on a specific ...

Adenosine is a natural substance manufacturers may use in cosmetic and skin care products. Evidence suggests that adenosine can soothe skin and support wound healing and the natural functioning of the ...

Adenosine kinase is an important enzyme that regulates both the intracellular and extracellular concentrations of adenosine. The inhibition of this enzyme has numerous clinical applications ranging ...