High point totals mean opportunity, and several key matchups stand out as potential fantasy goldmines in Week 10. Week 10 of the NFL season is already upon us, and the challenge of setting lineups and finding an edge in fantasy football only becomes greater than the week before.

Sigler projected the 0-4 Saints to quickly become sellers ahead of the Nov. 4 trade deadline. One of his potential moves has the 49ers sending third and fourth-round picks in the 2026 draft to New Orleans in exchange for 28-year-old Northern California native Carl Granderson.

The San Francisco 49ers have needs at both linebacker and edge rusher, and the New Orleans Saints reportedly could have one of each available at the trade deadline.

After one week back at home in Los Angeles, the Rams will be on the road again in Week 10 for a pivotal matchup with the San Francisco 49ers. It’s a rematch of their Week 5 game that went into overtime, only for the 49ers to win on a field goal and subsequent fourth-down stop in the final minutes.

Crafting the ideal trade offer the 49ers should send to the Saints to acquire star receiver Chris Olave before the 2025 deadline

In the second half, the Rams continued to pad their cushion by going up 34-10 on the Saints, making it look easy on both sides ... The Rams will hit the road after Sunday's win and face the rival 49ers in Week 10, a game that could see the return of ...

Jauan Jennings' name continues to come up in trade discussions. His latest move suggests he may finally be done with the Niners.

Logan Wilson, Trey Hendrickson and other players the 49ers need to target ahead of the 2025 NFL trade deadline

The San Francisco 49ers finished their Week 7 contest with a 20-10 win over the Atlanta Falcons on "Sunday Night Football" at Levi's® Stadium.

Find out how to watch the NFL Week 9 game between the San Francisco 49ers and New York Giants, as well as the latest odds and updated injury report.