Memphis football (6-1, 2-1 American) will host No. 20 USF (6-1, 3-0) in a game that will have a major impact on the conference title race. The Tigers are coming off a stunning upset loss at UAB, but a win here would put them right back into the conference title mix.

Memphis Tigers football coach Ryan Silverfield's team isn't a shoo-in for the American Championship Game, but they're the closest thing in the conference.

Our South Florida vs. Memphis picks, odds & expert predictions see the Tigers pulling off the home upset over the Bulls on Saturday, October 25, 2025.

Preview the Oct. 25 matchup between the South Florida Bulls and Memphis Tigers with predictions, odds, over/under, spread, betting lines and more.

No. 18 South Florida is the only ranked team in the AAC, but still ranks second in the conference standings. The Bulls will try to stay hot on Navy’s trail by s

Preview the Week 9 NCAA football matchup between the South Florida Bulls and Memphis Tigers with best bets, picks, predictions and more.

USF vs Memphis preview, prediction, and betting lines. It’s the battle to be the American Conference lead dog, with both trying to push for the College Football Playoff.

For all his dual-threat moxie and mobility, put on further dazzling display in a hostile environment Saturday afternoon, USF quarterback Byrum Brown still can’t seem to shoehorn his way into any plausible Heisman Trophy discussion.