Memphis football (6-1, 2-1 American) will host No. 20 USF (6-1, 3-0) in a game that will have a major impact on the conference title race. The Tigers are coming off a stunning upset loss at UAB, but a win here would put them right back into the conference title mix.

No. 18 South Florida is the only ranked team in the AAC, but still ranks second in the conference standings. The Bulls will try to stay hot on Navy’s trail by s

Memphis Tigers football coach Ryan Silverfield's team isn't a shoo-in for the American Championship Game, but they're the closest thing in the conference.

Alex Golesh and USF enter the matchup as the highest-ranked Group of Five team in college football, meaning it currently holds the inside track to a spot in the 12-team College Football Playoff. The Bulls have wins over then-No. 25 Boise State and then-No. 13 Florida on their resume.

Preview the Oct. 25 matchup between the South Florida Bulls and Memphis Tigers with predictions, odds, over/under, spread, betting lines and more.

Preview the Week 9 NCAA football matchup between the South Florida Bulls and Memphis Tigers with best bets, picks, predictions and more.

College football Week 9 odds, picks, predictions, TV channel, streaming for South Florida Bulls vs Memphis Tigers American game on Saturday, Oct. 25.

Our South Florida vs. Memphis picks, odds & expert predictions see the Tigers pulling off the home upset over the Bulls on Saturday, October 25, 2025.

On Saturday, the USF Bulls and Memphis Tigers will tussle in an American Athletic Conference battle at Simmons Bank Liberty Stadium.

Few games on the Week 9 slate carry more intrigue than South Florida versus Memphis, and college football analyst David Pollack made his stance clear on See Bal