Delivering a commencement speech at Dartmouth College, the actress said her "Grey's" tenure marked "one of the most challenging decades of my life."

Jeffrey Dean Morgan tells PEOPLE he was offered parts in movies, including 'P.S. I Love You' and 'Watchmen,' after his breakthrough performance as the dreamy heart transplant patient on ABC's hit medical drama 'Grey's Anatomy.

In a speech that had the 'Grey's Anatomy' actor discussing controversial diversity, inclusion and equity policies, the Canadian-born actress asked the college’s class of 2025: “Could I get deported?”

The actress shared with journalist Katie Couric the hilarious way she injured her foot before going on the red carpet.

Grey's Anatomy has been successfully running for over two decades and holds the unique distinction of being the longest-running primetime television show.

Grey’s Anatomy has featured some impressive guest stars come through over the last 21 seasons, and that likely won't change when Season 22 premieres on the 2025 TV schedule this fall. There are likely loads of celebs that are probably on everyone’s guest-star wish list,

Scott Speedman joined the cast of Grey’s Anatomy in Season 18, reprising the role of Dr. Nick Marsh from a one-episode guest appearance in Season 14. Many of the longtime series’ actors have said the surgical lingo is hard to nail down, but Speedman seems to actually enjoy it, as he said in Variety’s Actors on Actors series:

If Grey’s Anatomy has you hooked on messy love lives, high-stakes surgeries, and emotional rollercoasters in the break room, you’re not alone.

All 18 episodes of "Grey's Anatomy" Season 21 will be available to stream on Netflix on Saturday, June 14. Previous seasons of the show are available on the streaming platform as well. Season 21 of "Grey's Anatomy" is also available to stream on Hulu and Disney+.